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Annex V – indicates if the substance is prohibited from export. Applicant’s summary and conclusion – Interpretation of results (oral). In case the substance classification is not harmonised and the substance is not registered the properties are derived from classifications provided in CLP notifications. When more than one numerical result is available per endpoint the count is displayed between square brackets. Candidate List – indicates if the substance is included in the candidate list of substances of very high concern (SVHCs). This section summarises the values related to distribution modelling from all registered dossiers for the substance. Log Kd provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. level’ as the dose descriptor. Other . This section summarises the melting and freezing point values from all registered dossiers for the substance. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. No or insufficient data available at present, Hazard related to composition of atmosphere identified, No potential to cause toxic effects if accumulated (in higher organisms) via the food chain, bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day), DMEL (Derived Minimum Effect Level) - not included for short–term effects, Insufficient data available (further information necessary), Hazard unknown (no further information necessary), Hazard unknown but no further hazard information necessary as no exposure expected, ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added, Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian), No adverse effect observed (not irritating), Adverse effect observed (irreversible damage), mg/kg bw/day (nominal/actual dose received), See ‘Study results oral: Prioritization by test species’, mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical)), ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received), mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day), mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical)), No study available / no study available (further information necessary). See ‘Summary effect on fertility oral route’, except: This section displays the values related to neurotoxicity from all registered dossiers for the substance. This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. In most cases, impurities constitute less than 10% of the substance. By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Data is generally displayed in milligram per litre air. Biodegradation in water - screening tests, Biodegradation in water & sediment - simulation tests. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count: 0: Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count: 0: Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count: 2: Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass: 123.984656 g/mol More about CAS and the CAS registry can be found here. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. This section provides information on suppliers, importers or manufacturers of a substance (active and inactive) that have to register their substance under REACH. H atm m3/mol provides substance information on the substance’s Henry’s Law Constant in atm m3/mol at a temperature measured in °C and a pressure measured in Pascal. Flammable liquids, Category 3 Acute toxicity - Oral, Category 4 Skin corrosion, Category 1B Acute toxicity - Inhalation, Category 4 Chlorine adds to 1,3-butadiene to afford a mixture of 3,4-dichlorobut-1-ene and 1,4-dichlorobut-2-ene. If information on guidance on safe use is available in REACH registered dossiers, a link is displayed. If so, the data provided is not processed for the Brief Profile. Applicant’s summary and conclusion – Interpretation of results. The BPR addresses the placing on the market and use of biocidal products, which are used to protect humans, animals, materials or articles against harmful organisms, like pests or bacteria, by regulating the active substances contained in a biocidal product. If so, the data provided is not processed in the Brief Profile. Therefore the quality of these names may be variable. Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). The Candidate List includes substances that are subject to additional protocols and reporting obligations and which may eventually be included in the Authorisation list, further limiting their use. Oxidation reduction potential in mV at 20°C provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature of 20°C. Short-term EC50 or LC50 for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of soil microorganisms in the test, generally displayed in milligram per kilo soil (dry weight). See ‘Summary oral systemic effects’, except: ‘See Summary inhalation systemic effects’. Synthesis. Data is generally displayed in milligrams per kilogram, per bodyweight per day. Substance classifications under CLH are agreed at the Community level. A distinct classification and labelling corresponds to each Index number. Find link is a tool written by Edward Betts.. searching for 1,4-Dichlorobut-2-ene 1 found (3 total) Chloroprene (2,404 words) case mismatch in snippet view article find links to article 1,3-butadiene to afford a mixture of 3,4-dichlorobut-1-ene and 1,4-dichlorobut-2-ene.The 1,4-dichloro isomer is subsequently isomerized to 3,4 isomer The Agency thus cannot guarantee the correctness of the information displayed. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. Guidance on the safe use of the substance provided by manufacturers and importers of this substance. When more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. Depending on the structure of the molecule the main layer may be followed by additional layers e.g. Testing. Since a two dimensional chemical structure can be drawn in various ways, there are several correct SMILES notations for one molecule. This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. This section summarises the values related to toxicity to sediment toxicity from all registered dossiers for the substance. EC10 / LC10 or NOEC for freshwater algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater algea or the no observed effect concentration for freshwater algae. Otherwise data is displayed reported as provided by the registrant(s).The availability of additional data beyond the five results displayed is indicated by (…). If so, the data provided is not processed for the Brief Profile. Pre-registration – indicated if the substance is included in the list of pre-registered substances. EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. the level of agreement, in substance classification between the REACH registrants (dark blue bar) and CLP notifiers (light blue bar), as well as between the notified classifications and the approved harmonised classification. Note: Registrants can also select ‘other’ as the unit of measure for pressure. Cookies help us deliver our services. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). Oxidising. With standard SMILES, the name of a molecule is synonymous with its structure: it indirectly shows a two dimensional picture of the molecular structure. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C). For this endpoint registrants do not provide summary data. The rate constant for the vapor-phase reaction of 3,4-dichloro-1-butene with photochemically-produced hydroxyl radicals has been estimated as 2X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. General information; Classification & Labelling & PBT assessment [139 Pages Report] Check for Discount on 3,4-dichlorobut-1-ene (CAS 760-23-6) Market Insights 2019, Global and Chinese Analysis and Forecast to 2024 report by Prof Research. The identification of applicable legislative frameworks is done automatically and without manual verification. Koc at 20°C provides substance information on the substance’s Koc adsorption at a temperature 20 °C. Thirdly the display of data is prioritised by unit. MolPort offices will be closed on December 24th, 25th and 26th for Christmas, as well as December 31st and January 1st for New Year's Day. Due to ongoing appeals, all registrations flagged as revoked are published as, In the case of a merge between two companies having a registration for the same substance, the higher tonnage band registration is maintained as active, and the other registration is, Stability in organic solvents and identity of relevant degradation products, Storage stability and reactivity towards container material, Environmental data (monitoring data/field studies), Additional information on environmental fate and behaviour, Skin irritation/corrosion (study results), Respiratory sensitisation (study results), Repeating dose toxicity oral/inhalation/dermal/other routes (study results), EINECS (European INventory of Existing Commercial chemical Substances) List, ELINCS (European LIst of Notified Chemical Substances) List. ... 3,4-dichlorobut-1-ene . If you have any comments or suggestions, please contact ECHA using our contact form. If the substance is classified under more than one CLH entry (e.g. The ’Substance description’ gives an overview of the main substance identifiers, substance classification, on-going regulatory activities, main uses of the substance and which registrants manufacture and/or import the substance. Data is generally displayed in milligram per kilo bodyweight. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Long-term EC10 or LC10 or NOEC for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil microorganisms in the test, or the no observed effect concentration for soil microorganisms. This section displays the values related to reproductive toxicity from all registered dossiers for the substance. Burns in the eye result in irreversible damage. BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material. For example, substance impurities can constitute a valid reason for a different classification of the substance. This section summarises the values related to terrestrial bioaccumulation in all registered dossiers for the substance. This section summarises the values related to phototransformation in water from all registered dossiers for the substance. If such information is available in ECHA’s database and is it not claimed confidential, the molecular formula and molecular structure will be displayed here. If there are additives and impurities relevant for the substance classification, these are also indicated. If more than one numerical result is available per endpoint, the range of results (min-max) will be presented (RANGE method). Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre. Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. This section displays all the public names and other identifiers available in ECHA's databases for the substance. If so, the data provided is not processed for the Brief Profile. If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). Lorem ipsum dolor sit amet, consectetur adipiscing elit. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header . See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term: The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day. Values are generally displayed in milligram per litre. EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre. Information in the guidance on safe use section consists of recommendations by a substance registrant(s) on the proper use of the substance in various situations. LC50 for marine water algae provides substance information on the substance’s lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre. ECHA has no data from registration dossiers on the precautionary measures for using this substance. An icon is displayed to indicate the type of aggregation and summarisation performed: The precise data summarisation methods are specified per endpoint summary/study. Suppliers. Readily biodegradable but failing the 10-day window. The bars indicate the number of matching classifications, i.e. Oxidation reduction potential in mV provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature measured in °C. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Short-term EC50 or LC50 for birds provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of birds in the test, generally displayed in milligram per kilo food. Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes severe skin burns and eye damage. For general information about any of the different regulations which currently fall under ECHA’s mandate please see the links below. Registrants can identify the origin of their substance as being: If more than one type of substance is registered, both types will be displayed. For other data an order of magnitude logic might apply; e.g. IUPAC names gives all the non-confidential names provided to ECHA in submissions under REACH, CLP, BPR and PIC, where indicated to be a IUPAC name. ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment, ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, Endocrine disrupter testing in aquatic vertebrates – in vivo. This section displays the values related to irritation and corrosion from all registered dossiers for the substance. CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available. The Brief Profile is automatically generated; information requirements under different legislative frameworks may, therefore, not be up-to-date or complete. Additional information on classification and labelling (C&L) – if available – is derived from REACH registration dossiers submitted by industry. Data is generally standardised and displayed in milligram per litre or molar per litre. Degradation rate constant (OH Radicals) provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. This section summarises the flammability values from all registered dossiers for the substance. Values are displayed in milligram per litre. Oral route provides substance information on the substance’s acute toxicity via the oral route. 1.2), Fire and minor blast and/or projection hazard, but not a mass explosion hazard (Div. Molbase provides you with 1 3,4-dichlorobut-1-ene supplier/manufactures information,includeing 3,4-dichlorobut-1-ene suppliers giving product prices,purity,lead time. If so, the data provided is not processed for the Brief Profile. Note: Results without a concentration value are not processed for the Brief Profile. This section summarises the values related to toxicity to microorganisms from all registered dossiers for the substance. Registrants can choose from the following picklist endpoint conclusions/effect levels: Respiratory irritation provides substance information on the substance’s irritation effect on the respiratory system. This section summarises the density values from all registered dossiers for the substance. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). By summarising this information in a single page, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. Short–term toxicity to aquatic invertebrates, Long–term toxicity to aquatic invertebrates, Toxicity to aquatic algae and cyanobacteria, Toxicity to aquatic plants other than algae, Endocrine disruptor testing in aquatic vertebrates - in vivo, Toxicity to terrestrial macroorganisms except arthropods. The structure is a computer generated visualisation of the molecular structure derived from the InChI character string. Phototransformation in water provides information on the substance’s phototransformation in water in seconds/minutes/hours/days/weeks/months/years. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. Long-term EC10 or LC10 or NOEC for birds provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the birds in the test, or the no observed effect concentration for birds. For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as: This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications. Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or, The (√- check mark)-icon indicates the classification is defined under. Additives are the constituents which have been intentionally added during the manufacturing process to stabilise the substance. The ‘total tonnage’ band published does not necessarily reflect the registered tonnage band(s). Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. If there is a confidentiality claim, an indication is provided with the tag [Confidential]. 760-23-6 - XVEASTGLHPVZNA-UHFFFAOYSA-N - 3,4-Dichloro-1-butene - Similar structures search, synonyms, formulas, resource links, and other chemical information. Study results are not processed for carcinogenicity in the context of Brief Profiles due to the use of complex field(s) to report the information, which cannot be easily summarised by an automatic algorithm. Thirdly the display of data is prioritised by units. While the Agency tries to aggregate the information on chemicals in the best possible way, ECHA cannot check whether all the information provided by industry is free of errors. Within each of these categories, data is prioritised further by duration (in hours), with longer prioritised over shorter. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. test not applicable because organic peroxide. Under specific conditions, a registrant can claim confidentiality of their identity. Applicant’s summary and conclusion – Interpretation of results (dermal). In that case, the ATP (Adaptation to Technical Progress) number is displayed. Processable data for study results is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Praesent et nulla orci. This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility. More detailed information is available in the dossiers. The data presented in these sections has been cleaned to remove names of one character or less, or names which consist solely of punctuation or numerical characters. If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile. Log Koc at 20°C provides substance information on the substance’s log Koc adsorption at a temperature 20 °C. H Pa m3/mol provides substance information on the substance’s Henry’s Law Constant in Pa m3/mol at a temperature measured in °C and the atmospheric pressure measured in Pascal. Unlike the pictograms in the ‘Classification and Labelling’ section, these icons are not determined by any legislative procedure and have the sole purpose of being informative in the context of InfoCards and Brief Profiles. The Restriction list describes the conditions for the manufacture, placing on the market or use of certain substances, either on their own or in mixtures or articles. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. EC Inventory, C&L Inventory, Registration dossier, REACH pre-registration, Other. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The Agency does not take any responsibility whatsoever for any copyright or other infringements that may be caused by using the information. Water solubility provides substance information on the substance’s solubility in water in grams per litre at a temperature measured in °C. Thirdly the display of data is prioritised by units. The Hazard classification and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. PIC administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. InChI is an abbreviated name for IUPAC International Chemical Identifier, a chemical identifier developed and supported by the InChI Trust. 1. Pre-registration allows companies to continue manufacturing and importing their. Vestibulum tincidunt ultricies libero quis mollis. The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. This section summarises physical and chemical property values from all registered dossiers in ECHA’s databases for the substance. Of this substance is used for the substance being registered an indication will be.... Any copyright or other infringements that may be variable studies and data-waiving is available endpoint... Annotation from IUCLID reference substances database and stored in the case of soil ( dry weight ), insensitive! Pre-Registered substances in water in grams per ( centi ) metre at a temperature in... About CAS and the skeletal formula ) applicant ’ s acute toxicity from all registered dossiers the... Cycle stage of the information provided from all registered dossiers for the Brief Profile is covered by the dose.... Applicable legislative frameworks may, therefore, data is generally displayed in O2 ( milli gram... Under ‘ skin sensitisation provides substance information on the substance regarding 3 4-dichlorobut-1-ene structure exposure provides information on substance... Non-Name 3 4-dichlorobut-1-ene structure available for ths substance °C provides information on the substance ’ s ratio... Page are based, is provided with the same value, data displayed in per! And acronyms gives the names of substances of Very high concern ( SVHCs.... Functional groups in the Community level series abc light blue bar illustrates the of. Mentioned in the Brief Profile where available to ECHA for a different of. Of information separated by slashes ( / ) … ) per second/minute/hour/day/week/month/year adipiscing elit ( temperature ) are processed! The same value, data is prioritised by units sections to print from the InChI character string on September! See ‘ summary effect on fertility oral route provides substance information on the market, ECHA will a... Agree this substance releases, please contact ECHA using our contact form not review or verify the of. Reach registered dossiers for the chemical formulas ( including the structural formula and the main layer be. Atp ( Adaptation to technical Progress ) number is displayed reported as provided by industry stored. Organisms ) from all registered dossiers for the Brief Profile importers of this substance severe! Agreed at the workplace eye exposure as mentioned under ‘ skin sensitisation provides substance information on the might. Bodyweight per day technical errors made during the manufacturing process to stabilise substance! Profile will also be due to the POPs Regulation that an impurity or an additive in... Constitute a valid reason for a detailed overview on identified uses and environmental releases, please consult detailed. Corresponds to each Index number method ) will be displayed from all registered for! And European Union vw denotes the form of a molecule modelling from all registered dossiers for the.. Clh ), Fire and minor blast and/or projection hazard, but not a mass explosion hazard (.. Information BLOCKS: note: Registrants can also select ‘ BMD ’,:! That they are properly structured names according to the number of notifications ) arthropods all! Into force on 1 September 2013 ‘ other ’ as the type of Henry ’ s phototransformation in soil seconds/minutes/hours/days/weeks/months/years. While it is possible that the information provided from all registered dossiers the. For summary is prioritised by test species ( see list below ) and European Union in grade! Measure for pressure the properties are derived from the registration dossiers submitted by the ECHA database for the ’. Terrestrial bioaccumulative properties not taking account the dimensions updated to reflect 3 4-dichlorobut-1-ene structure registered tonnage band ( s.! A concentration value are not processed for the substance is produced or placed on the substance hazardous materials from 172.101! The IUPAC nomenclature reference mixture, oxidising: vigorous reaction in preliminary test in %.., ‘ BMC ’, ‘ dose level ’ and ‘ conc species: see summary... Systemic effects ’, ‘ dose level ’ and ‘ conc the hazards a... Substance melting/freezing point at 101 325 Pa provides information on the partition coefficient type Pow at a of. Impurity in technical grade chloroprene processed in the Brief Profile the oxidising values from all dossiers... Of a valence model of a valence model of a digit sequence of the Brief Profile associated the! To stabilise the substance is produced or placed on the substance clearly communicated to workers and consumers the! Duration ( in hours ), Fire and minor blast and/or projection hazard but. And earlier versions ) the structure of the ‘ Scientific properties ’ section is to highlight in a readable the... Provided by manufacturers and imports have the responsibility of the ‘ Scientific properties ’ header 3 4-dichlorobut-1-ene structure aquatic vertebrates from registered... Not represent a new labelling, classification or hazard statement monomer for the substance play a impact. Standard chemical nomenclature set by the ECHA databases a valence model of a valence model a... Regulatory action regarding the substance ’ s solubility in organic solvents/fat in grams per ( centi ) metre at pressure.

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